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Antimicrobial effects of allicin and ketoconazole on trichophyton rubrum under in vitro condition BJM
Aala,Farzad; Yusuf,Umi Kalsom; Jamal,Farida; Rezaie,Sassan.
Dermatophytosis is caused by a group of pathogenic fungi namely, dermatophytes, is among the most prevalent infectious diseases worldwide. Azole drugs are widely used in the treatment of dermatomycosis, but can cause various side effects and drug resistance to the patients. Hence, for solving this problem can be used from the plant extract as alternative for chemical drugs. Allicin is a pure bioactive compound isolated from garlic was tested for its potential as a treatment of dermatomycosis in this study. This study evaluated the in vitro efficacy of pure allicin against ten isolates of Trichophyton rubrum and the MIC50 and MIC90 ranged from 0.78-12.5 µg/ml for allicin. The results revealed that the order of efficacy based on the MICs values, all isolates...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Allicin; Antifungal drugs; Dermatophytes; MIC (minimal inhibitory concentration.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822012000200044
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Biosynthesis of selenium nanoparticles using Klebsiella pneumoniae and their recovery by a simple sterilization process BJM
Fesharaki,Parisa Jafari; Nazari,Pardis; Shakibaie,Mojtaba; Rezaie,Sassan; Banoee,Maryam; Abdollahi,Mohammad; Shahverdi,Ahmad Reza.
The use of biologically derived metal nanoparticles for various proposes is going to be an issue of considerable importance; thus, appropriate methods should be developed and tested for the biological synthesis and recovery of these nanoparticles from bacterial cells. In this research study, a strain of Klebsiella pneumoniae was tested for its ability to synthesize elemental selenium nanoparticles from selenium chloride. A broth of Klebsiella pneumoniae culture containing selenium nanoparticles was subjected to sterilization at 121ºC and 17 psi for 20 minutes. Released selenium nanoparticles ranged in size from 100 to 550 nm, with an average size of 245 nm. Our study also showed that no chemical changes occurred in selenium nanoparticles during the wet...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Selenium nanoparticles; Sterilization; Klebsiella pneumoniae; Synthesis; Recovery.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822010000200028
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